The best treatment for equine gastric ulcer syndrome is a natural, grazing lifestyle…all pasture, all the time. But this is not practical or possible in many cases so horse owner turn to medications.
Equine gastric ulcer syndrome (EGUS) affects a large number of horses. EGUS is associated with stress and symptoms can develop within 5 days of a stressful event.
Stress? What stress?
Stressful events include lengthy transport, surgery, race training, isolation and limited turnout, overuse of NSAIDs and improper feeding techniques.
• Up to 93 percent of racehorses show signs of EGUS.
• Between 40 and 60 percent sport horses suffer ulcers.
Proton Pump Inhibitors
Proton pumps are the mechanism responsible for the product of acid that forms in the stomach. They are the final step in a long process that causes ulcers. Proton pump inhibitors prevent these cellular pumps from doing their dastardly deed. Omedprazole, the equine version of Prilosec, is sold under the brand name Gastrogard®. Gastrogard® is approved by the FDA as a treatment for EGUS. It is easy to feed and given once a day. It is the most popular treatment for EGUS.
H2 Blockers
Histamines are secreted by body tissue and stimulate the stomach cells to produce acid. H2 blockers block the production of histamine, slowing the rate of acid production. Cimetidine (Tagamet), ranitidine (Zantac) and famotidine (Pepcid AC) are H2 blockers.
Antacids
Antacids neutralize stomach acid that has already been produced.

